Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | GRM6 | O15303 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203259 | 0.97 | CYP2C19 (0.35) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL27601761 | 0.94 | GRM4 (0.33) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL29280477 | 0.94 | GRM4 (0.33) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL27620337 | 0.94 | GRM4 (0.33) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL3176795 | 0.74 | GRM4 (0.37) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL6686381 | 0.73 | CYP2C19 (0.35) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL4291628 | 0.71 | SMN1; SMN2 (0.35) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL27788454 | 0.71 | GRM4 (0.35) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 | |
| SCHEMBL25475447 | 0.71 | — | — | |
| SCHEMBL11537183 | 0.71 | GRM1 (0.43) | GRM4CYP2C19GRM6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163323-B | Synthesis method of 3-oxo-cyclobutanecarboxylic acid | 大连双硼医药化工有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-114163323-A | Synthetic method of 3-oxocyclobutanecarboxylic acid | 大连双硼医药化工有限公司 | 2022-03-11 | — | — | CN | disclosed |