Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.68 |
| ▸ | PGR | P06401 | 8/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203512 | 0.88 | NR3C1 (0.69) | NR3C1PGRNR3C2 | |
| SCHEMBL4207284 | 0.82 | NR3C1 (0.75) | NR3C1PGRNR3C2 | |
| SCHEMBL14269098 | 0.81 | NR3C1 (1.00) | NR3C1PGRNR3C2 | |
| SCHEMBL3699419 | 0.78 | NR3C1 (0.73) | NR3C1PGRNR3C2 | |
| SCHEMBL1933453 | 0.78 | NR3C1 (0.63) | NR3C1PGRNR3C2 | |
| SCHEMBL5798637 | 0.78 | NR3C1 (0.78) | NR3C1PGRNR3C2 | |
| SCHEMBL4203191 | 0.78 | NR3C1 (0.87) | NR3C1PGRNR3C2 | |
| SCHEMBL1930963 | 0.76 | NR3C1 (0.61) | NR3C1PGRNR3C2 | |
| SCHEMBL4906857 | 0.75 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL291109 | 0.74 | NR3C1 (0.78) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |