Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.69 |
| ▸ | PGR | P06401 | 7/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203394 | 0.88 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL4197570 | 0.83 | NR3C1 (0.76) | NR3C1PGRNR3C2 | |
| SCHEMBL4195130 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2 | |
| SCHEMBL3693045 | 0.80 | NR3C1 (0.66) | NR3C1PGRNR3C2 | |
| SCHEMBL5779187 | 0.80 | NR3C1 (0.58) | NR3C1PGRNR3C2 | |
| SCHEMBL4208932 | 0.79 | NR3C1 (0.88) | NR3C1PGRNR3C2 | |
| SCHEMBL5780295 | 0.79 | NR3C1 (0.79) | NR3C1PGRNR3C2 | |
| SCHEMBL291694 | 0.76 | NR3C1 (1.00) | NR3C1PGRNR3C2 | |
| SCHEMBL5822764 | 0.76 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL1634863 | 0.76 | NR3C1 (0.70) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |