Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6139684 | 0.97 | CYP19A1 (0.48) | CYP19A1BRD4ALDH1A1LIPEMAPT | |
| SCHEMBL5206971 | 0.87 | CYP19A1 (0.47) | CYP19A1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6139688 | 0.82 | CYP19A1 (0.45) | CYP19A1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7606232 | 0.82 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL7606241 | 0.81 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL7611458 | 0.80 | APP (0.42) | CYP19A1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7611451 | 0.80 | APP (0.42) | CYP19A1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5205310 | 0.78 | ALDH1A1 (0.40) | CYP19A1ALDH1A1TDP1 | |
| SCHEMBL5205302 | 0.78 | ALDH1A1 (0.40) | CYP19A1ALDH1A1TDP1 | |
| SCHEMBL7467733 | 0.74 | CYP19A1 (0.44) | CYP19A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | disclosed |