Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287375 | 0.90 | KEAP1 (0.42) | CYP19A1ELANEL3MBTL1CYP2C9EGFR | |
| SCHEMBL5681907 | 0.88 | HPGD (0.39) | CYP19A1ELANEL3MBTL1EGFRF2 | |
| SCHEMBL5206971 | 0.87 | CYP19A1 (0.47) | CYP19A1ELANEL3MBTL1CYP2C9EGFR | |
| SCHEMBL5203170 | 0.87 | NPC1 (0.38) | CYP19A1L3MBTL1EGFRSMN1; SMN2APP | |
| SCHEMBL8817183 | 0.85 | NQO2 (0.40) | ELANEL3MBTL1F2MAPTSMN1; SMN2 | |
| SCHEMBL1934979 | 0.82 | GPBAR1 (0.45) | CYP19A1L3MBTL1 | |
| SCHEMBL5203422 | 0.81 | MEN1 (0.40) | CYP19A1MAPTSMN1; SMN2TDP1APP | |
| SCHEMBL3142761 | 0.81 | MEN1 (0.40) | CYP19A1MAPTSMN1; SMN2TDP1APP | |
| SCHEMBL3142767 | 0.81 | MEN1 (0.40) | CYP19A1MAPTSMN1; SMN2TDP1APP | |
| SCHEMBL3286247 | 0.77 | KEAP1 (0.43) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |
| CN-1159797-A | Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof | SMITHKLINE BEECHAM PLC (GB) | 1997-09-17 | — | — | CN | disclosed |