Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204078 | 1.00 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5202290 | 0.88 | MEN1 (0.53) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5202292 | 0.88 | MEN1 (0.53) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5202286 | 0.88 | MEN1 (0.53) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5206340 | 0.88 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5202737 | 0.88 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5204522 | 0.85 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5204527 | 0.85 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7165140 | 0.84 | KMT2A (0.51) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7165995 | 0.83 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223944-B1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2007-01-03 | — | — | EP | claimed |
| US-6552008-B1 | Administering effective amount of a selected azo-pyrazole derivative for therapy of thrombocytopenia | SMITHKLINE BEECHAM CORPORATION | 2003-04-22 | — | — | US | claimed |
| JP-2003509462-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1223944-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | EP | claimed |
| EP-1223944-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-07-24 | — | — | EP | claimed |
| WO-2001021180-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-29 | — | — | WO | claimed |
| EP-1223944-B1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2007-01-03 | — | — | EP | disclosed |
| US-6552008-B1 | Administering effective amount of a selected azo-pyrazole derivative for therapy of thrombocytopenia | SMITHKLINE BEECHAM CORPORATION | 2003-04-22 | — | — | US | disclosed |
| EP-1223944-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1223944-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001021180-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-29 | — | — | WO | disclosed |