Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165991 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL7165988 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5202737 | 0.86 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5206340 | 0.86 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5206330 | 0.86 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL7178572 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5204074 | 0.83 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5204078 | 0.83 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5204527 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL5204522 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552008-B1 | Administering effective amount of a selected azo-pyrazole derivative for therapy of thrombocytopenia | SMITHKLINE BEECHAM CORPORATION | 2003-04-22 | — | — | US | disclosed |