Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1912644 | 0.83 | AKR1C3 (0.51) | AKR1C3AKR1C2AKR1C1PTGS1MMEL1 | |
| SCHEMBL29091322 | 0.83 | PPARG (0.49) | PPARGPPARAAKR1C3AKR1C2ITGB1 | |
| SCHEMBL11845407 | 0.81 | PPARG (0.54) | PPARGPPARAAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL3677263 | 0.81 | AKR1C3 (0.66) | PPARGPPARAAKR1C3AKR1C2AKR1C1 | |
| Xenbucin SCHEMBL24134 | 0.80 | PTGS2 (0.58) | AKR1C3AKR1C2AKR1C1PTGS1LMNA | |
| SCHEMBL11849673 | 0.79 | AKR1C3 (0.53) | PPARGPPARAAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL28460308 | 0.79 | AKR1C3 (0.62) | PPARGPPARAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28966214 | 0.79 | PPARG (0.53) | PPARGPPARAAKR1C3AKR1C2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7228142 | 0.77 | PPARG (0.45) | PPARGPPARAAKR1C3AKR1C2ITGB1 | |
| Xenbucin SCHEMBL3360074 | 0.77 | PTGS2 (0.55) | AKR1C3AKR1C2AKR1C1PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |