Xenbucin

Xenbucin

SCHEMBL24134

CCC(C(=O)O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.58
AKR1C3 P42330 6/20 0.54
AKR1C2 P52895 6/20 0.54
MAPT P10636 2/20 0.50
HTR1A P08908 1/20 0.50
ADRA1A P35348 1/20 0.50
KCNQ2 O43526 1/20 0.50
AKR1C1 Q04828 1/20 0.49
PTGS1 P23219 1/20 0.49
LMNA P02545 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CTSS P25774 1/20 0.48
CTSK P43235 1/20 0.48
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xenbucin SCHEMBL3360074 0.96 PTGS2 (0.55) PTGS2AKR1C3AKR1C2MAPTHTR1A
Xenbucin SCHEMBL10345475 0.89 PTGS2 (0.51) PTGS2AKR1C3AKR1C2MAPTHTR1A
SCHEMBL65737 0.88 LMNA (0.59) MAPTHTR1AADRA1AKCNQ2LMNA
SCHEMBL20769804 0.88 LMNA (0.59) MAPTHTR1AADRA1AKCNQ2LMNA
SCHEMBL29757088 0.88 LMNA (0.59) MAPTHTR1AADRA1AKCNQ2LMNA
SCHEMBL67237 0.88 LMNA (0.59) MAPTHTR1AADRA1AKCNQ2LMNA
SCHEMBL1715 0.88 LMNA (0.59) MAPTHTR1AADRA1AKCNQ2LMNA
SCHEMBL1574429 0.88 AKR1C3 (0.58) PTGS2AKR1C3AKR1C2HTR1AADRA1A
SCHEMBL4558922 0.87 PTGS2 (0.52) PTGS2MAPTKCNQ2LMNAHSD17B10
Xenbucin SCHEMBL10345476 0.86 PTGS2 (0.45) PTGS2AKR1C3AKR1C2MAPTHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3145 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4470565-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT OnQuality Pharmaceuticals China Ltd. (CN) 2024-12-04 EP claimed
CN-118742325-A Methods for preventing or treating diseases or conditions associated with antineoplastic agents 上海岸阔医药科技有限公司 2024-10-01 CN claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
WO-2023179008-A1 VEGETABLE OIL-BASED LOW-HALOGEN ENVIRONMENTALLY FRIENDLY INK AND PREPARATION METHOD THEREFOR 中山市富日印刷材料有限公司 2023-09-28 WO claimed
WO-2023142996-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT 上海岸阔医药科技有限公司 2023-08-03 WO claimed
EP-3795721-B1 NANOWIRE STRUCTURE TO FORM AN ARRAY OF ISOLATED CAPACITORS, AND ASSOCIATED MANUFACTURING METHODS MURATA MANUFACTURING CO (JP) 2023-07-19 EP claimed
CN-115141474-A PC composite material with stable coloring and preparation method thereof 合肥杰事杰新材料股份有限公司 2022-10-04 CN claimed
US-20210145763-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD. (AU) 2021-05-20 US claimed
WO-2021054927-A2 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2021-03-25 WO claimed
EP-2841066-B1 ANTI-INFLUENZA AGENT CONJUGATED TO ANTI-INFLAMMATORY AGENT ACADEMIA SINICA (TW) 2021-02-17 EP claimed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
US-5179097-A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids ANGRES ISAAC A (US) 1993-01-12 US claimed
EP-0171084-B1 PHARMACEUTICAL OIL-IN-WATER TYPE MICRO-EMULSION LEDERLE (JAPAN) LTD. (JP) 1991-06-05 EP claimed
US-4347373-A Derivatives of 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole TURCONI FRANCO 1982-08-31 US claimed
EP-0036684-A1 Derivatives of 4-methyl-5-(2-aminoethyl)-thiomethyl-imidazole having therapeutic activity Turconi, Franco (IT) 1981-09-30 EP claimed