Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 16/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674643 | 0.90 | CCR5 (0.68) | CCR5MCHR1 | |
| SCHEMBL5208758 | 0.90 | CCR5 (0.68) | CCR5MCHR1 | |
| SCHEMBL5211618 | 0.89 | CCR5 (0.69) | CCR5MCHR1 | |
| SCHEMBL7674608 | 0.83 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5205976 | 0.83 | CCR5 (0.58) | CCR5MCHR1 | |
| SCHEMBL5209488 | 0.82 | CCR5 (0.69) | CCR5MCHR1 | |
| SCHEMBL5203702 | 0.81 | CCR5 (0.69) | CCR5 | |
| Iodide SCHEMBL7682596 | 0.81 | CCR5 (0.83) | CCR5 | |
| SCHEMBL5208454 | 0.77 | CCR5 (0.70) | CCR5MCHR1 | |
| SCHEMBL5207505 | 0.77 | CCR5 (0.74) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |