Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208758 | 1.00 | CCR5 (0.68) | CCR5MCHR1CXCR5CXCR3 | |
| SCHEMBL5211618 | 0.99 | CCR5 (0.69) | CCR5MCHR1CXCR5CXCR3 | |
| SCHEMBL5205976 | 0.92 | CCR5 (0.58) | CCR5MCHR1 | |
| SCHEMBL5209488 | 0.91 | CCR5 (0.69) | CCR5MCHR1CXCR3 | |
| SCHEMBL5203702 | 0.90 | CCR5 (0.69) | CCR5CXCR5CXCR3 | |
| SCHEMBL5204517 | 0.90 | CCR5 (0.58) | CCR5MCHR1 | |
| SCHEMBL7674608 | 0.90 | CCR5 (0.69) | CCR5CXCR5CXCR3 | |
| SCHEMBL5208454 | 0.87 | CCR5 (0.70) | CCR5MCHR1CXCR3 | |
| SCHEMBL5209767 | 0.86 | CCR5 (0.73) | CCR5CXCR5CXCR3 | |
| SCHEMBL5207505 | 0.84 | CCR5 (0.74) | CCR5CXCR5CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |