Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659254 | 0.79 | SCN9A (0.37) | KDM4EPARP1MEN1KMT2AMAP2K2 | |
| SCHEMBL23772003 | 0.77 | L3MBTL1 (0.36) | KDM4EPARP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL715572 | 0.75 | CA12 (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL69773 | 0.74 | NOTUM (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL5175113 | 0.70 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL17144775 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29002489 | 0.69 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL10103745 | 0.69 | NR4A2 (0.48) | KDM4EALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL5176186 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL15051286 | 0.67 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819701-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058630-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-08 | — | — | WO | disclosed |