Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.69 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066614 | 0.94 | FFAR1 (0.70) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| Hydrochloric Acid SCHEMBL10622121 | 0.93 | FFAR1 (0.68) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| SCHEMBL4222632 | 0.93 | FFAR1 (0.68) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.93 | FFAR1 (0.68) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| SCHEMBL1756380 | 0.90 | FFAR1 (0.72) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| SCHEMBL5205577 | 0.90 | FFAR1 (0.72) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| SCHEMBL6341082 | 0.90 | FFAR1 (0.68) | FFAR1FFAR4ALOX5AKR1B1NR4A1 | |
| SCHEMBL6238323 | 0.87 | ALDH1A1 (0.73) | FFAR1FFAR4ALOX5ALDH1A1MAPT | |
| SCHEMBL9659998 | 0.84 | FFAR1 (0.71) | FFAR1FFAR4ALOX5APPSRD5A2 | |
| SCHEMBL3498840 | 0.84 | NR4A2 (0.71) | FFAR1APPNR4A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115427409-A | Pyrimidin-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2022-12-02 | — | — | CN | disclosed |
| CN-110407727-B | Method for preparing alkyl trifluoromethyl selenide | 武汉理工大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-110407727-A | A method of preparing alkyl trifluoromethyl selenide | UNIV WUHAN TECH | 2019-11-05 | — | — | CN | disclosed |
| US-20140364398-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-8853258-B2 | C-linked hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | HAX1, LPXN, AGXT | FFAR1 1313/4885FFAR4 2386/4885ALOX5 653/4885 |
| US-20140364398-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | LCT, AGXT, PRXL2A | FFAR1 2319/4885FFAR4 2899/4885ALOX5 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.