Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280738 | 0.83 | MCHR1 (0.42) | MCHR1MAOBMAPK14 | |
| SCHEMBL5204609 | 0.83 | MCHR1 (0.38) | HTR2AHTR2CSLC6A4PREPMCHR1 | |
| SCHEMBL5205590 | 0.81 | MAOB (0.39) | MAOBMAPK14 | |
| SCHEMBL5209399 | 0.81 | MAPK14 (0.43) | HTR6MAPK14 | |
| SCHEMBL5204460 | 0.79 | NMT2 (0.40) | HTR2AHTR2CSLC6A4PREPMCHR1 | |
| SCHEMBL5207452 | 0.79 | MEN1 (0.39) | MAOBMAPK14 | |
| SCHEMBL5203024 | 0.79 | MAOB (0.37) | HTR2AHTR2CSLC6A4MAOBMAPK14 | |
| SCHEMBL3526249 | 0.72 | MAPK14 (0.49) | MAOBMAPK14 | |
| SCHEMBL3521563 | 0.71 | MAPK14 (0.55) | MAOBMAPK14 | |
| SCHEMBL3523245 | 0.69 | HTR2A (0.47) | HTR2AHTR2CSLC6A4GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |