Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057594 | 0.98 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL12057608 | 0.98 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL14156328 | 0.82 | MEN1 (0.51) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL13151080 | 0.81 | ADORA1 (0.70) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL351385 | 0.81 | ADORA1 (0.55) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL14156287 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL2688221 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL644159 | 0.78 | ALDH1A1 (0.73) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL8290416 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL10713938 | 0.76 | ALDH1A1 (0.71) | ALDH1A1MAPTHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |