Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 7/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485336 | 0.98 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL11479163 | 0.96 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2688221 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10713938 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8290416 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3656064 | 0.82 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8199267 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3397070 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8189546 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10851877 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042610-A1 | PIFITHRIN ANALOGUES AND METHODS OF TREATING RETT SYNDROME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-119161334-A | Amide derivative containing thiophene structure, preparation method and application thereof | 贵州大学 | 2024-12-20 | — | — | CN | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-3131890-B1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | PASTEUR INSTITUT KOREA (KR) | 2019-04-24 | — | — | EP | disclosed |
| US-9809602-B2 | Compounds for treating viral infections | INSTITUT PASTEUR KOREA (KR) | 2017-11-07 | — | — | US | disclosed |
| US-9809602-B2 | Compounds for treating viral infections | INSTITUT PASTEUR KOREA (KR) | 2017-11-07 | — | — | US | disclosed |
| US-9604977-B2 | Bicyclic thiophenylamide compounds | HOFFMAN-LA ROCHE INC. (US) | 2017-03-28 | — | — | US | disclosed |
| EP-0586663-B1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LTD (GB) | 1999-09-29 | — | — | EP | disclosed |
| US-5519015-A | BACTERICIDES | ZENECA LIMITED (GB) | 1996-05-21 | — | — | US | disclosed |
| EP-0586663-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993019070-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3997545-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-12-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | TSLP, CYSLTR1, CYSLTR2 | ALDH1A1 233/4885MAPT 2356/4885KDM4E 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.