Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23064534 | 0.93 | ESR1 (0.58) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL523273 | 0.88 | ESR1 (0.62) | ESR1ESR2MEN1KMT2ACYP2C9 | |
| SCHEMBL13921507 | 0.83 | ESR1 (0.84) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL29975007 | 0.80 | L3MBTL1 (0.56) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL1997854 | 0.80 | L3MBTL1 (0.56) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL15841547 | 0.73 | GFER (0.60) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL15841548 | 0.73 | GFER (0.60) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL10574313 | 0.71 | HDAC6 (0.56) | ESR1ESR2MAPTTSHRALDH1A1 | |
| SCHEMBL22691666 | 0.71 | CA1 (0.51) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3739324 | 0.70 | HDAC6 (0.54) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362855-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-7045515-B2 | β-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| US-20040063929-A1 | Beta-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1362855-A1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063929-A1 | Beta-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | HMGCR, NCEH1, CETP | ESR1 4128/4885ESR2 2902/4885MEN1 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.