SCHEMBL29975007

SCHEMBL29975007

COc1ccc([C@@H]2CC(=O)N2c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.56
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
GFER P55789 1/20 0.53
ALDH1A1 P00352 7/20 0.52
ABAT P80404 1/20 0.52
MAPK1 P28482 2/20 0.51
HSD11B1 P28845 1/20 0.49
MAPT P10636 3/20 0.48
ATM Q13315 3/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 2/20 0.47
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
S1PR4 O95977 1/20 0.47
S1PR1 P21453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997854 1.00 L3MBTL1 (0.56) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL15841548 0.94 GFER (0.60) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL15841547 0.94 GFER (0.60) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL2800404 0.92 ESR1 (0.63) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL14674682 0.86 ESR1 (0.51) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL10572076 0.86 ALDH1A1 (0.54) L3MBTL1GFERALDH1A1ABATATM
SCHEMBL14412033 0.85 KMT2A (0.62) L3MBTL1ESR1ESR2GFERALDH1A1
SCHEMBL523273 0.84 ESR1 (0.62) ESR1ESR2GFERALDH1A1ATM
SCHEMBL31409167 0.81 RAB9A (0.51) L3MBTL1GFERALDH1A1ABATMAPT
SCHEMBL1995264 0.80 TUBB4A (0.54) L3MBTL1ESR1ESR2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135331-A Rhodospirillum rubrum cells for lowering plasma cholesterol while leaving other serum protein levels unaffected 埃兹科尔公司 2022-09-30 CN disclosed