SCHEMBL5205889

SCHEMBL5205889

[CH2]CCC(=O)N(C)C(C)CC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA4 P43681 1/20 0.34
NPY5R Q15761 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5211212 0.88 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL5204440 0.83 NPY5R (0.35) CHRNB2CHRNB4CHRNA4NPY5R
SCHEMBL5208821 0.81 CHRNB2 (0.31) CHRNB2CHRNB4CHRNA4
SCHEMBL5208413 0.80 CHRNB2 (0.33) CHRNB2CHRNB4CHRNA4ALDH1A1
SCHEMBL24654932 0.79 CHRNB2 (0.34) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL15691911 0.79 CHRNB2 (0.34) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL8305409 0.78 ACACB (0.41) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL23612991 0.78 ACACB (0.41) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL23612995 0.78 ACACB (0.41) CHRNB2CHRNB4CHRNA4NPY5RALDH1A1
SCHEMBL5203858 0.78 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed