Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211095 | 1.00 | KCNH2 (0.48) | KCNH2CYP2D6LMNAKDM4EPIK3CD | |
| SCHEMBL7728974 | 0.91 | KCNH2 (0.50) | KCNH2CYP2D6LMNAKDM4EPIK3CD | |
| SCHEMBL5185294 | 0.88 | CYP2D6 (0.51) | KCNH2CYP2D6LMNAKDM4EALDH1A1 | |
| SCHEMBL6705647 | 0.87 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL449105 | 0.87 | KCNH2 (0.52) | KCNH2CYP2D6LMNAKDM4EPIK3CD | |
| SCHEMBL449104 | 0.87 | KCNH2 (0.52) | KCNH2CYP2D6LMNAKDM4EPIK3CD | |
| SCHEMBL5207282 | 0.86 | MTNR1A (0.43) | KCNH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5214162 | 0.86 | MTNR1A (0.43) | KCNH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5736765 | 0.79 | CYP2D6 (0.49) | KCNH2CYP2D6LMNAKDM4EALDH1A1 | |
| SCHEMBL5736772 | 0.79 | CYP2D6 (0.49) | KCNH2CYP2D6LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484328-B1 | Derivatives of quinolyl-propyl-piperidine and their use as antimicrobial agents | AVENTIS PHARMA SA (FR) | 2007-05-02 | — | — | EP | disclosed |
| EP-1484328-A1 | Derivatives of quinolyl-propyl-piperidine and their use as antimicrobial agents | Aventis Pharma S.A. (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |