Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206227 | 0.91 | KCNH2 (0.48) | KCNH2LMNAKDM4ECYP2D6PIK3CD | |
| SCHEMBL5211095 | 0.91 | KCNH2 (0.48) | KCNH2LMNAKDM4ECYP2D6PIK3CD | |
| SCHEMBL6705647 | 0.90 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL449105 | 0.87 | KCNH2 (0.52) | KCNH2LMNAKDM4ECYP2D6PIK3CD | |
| SCHEMBL449104 | 0.87 | KCNH2 (0.52) | KCNH2LMNAKDM4ECYP2D6PIK3CD | |
| SCHEMBL5185294 | 0.87 | CYP2D6 (0.51) | KCNH2LMNAKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL7724410 | 0.86 | KCNH2 (0.54) | KCNH2LMNAKDM4ECYP2D6PREP | |
| SCHEMBL7725186 | 0.86 | MTNR1A (0.43) | KCNH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5207267 | 0.83 | KCNH2 (0.59) | KCNH2LMNAKDM4ECYP2D6PREP | |
| SCHEMBL5187841 | 0.81 | KCNH2 (0.52) | KCNH2LMNAKDM4ECYP2D6PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |