Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5202539 | 0.94 | ALDH1A1 (0.38) | KMT2AMEN1GAAMAPTTPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5205888 | 0.93 | ALDH1A1 (0.37) | KMT2AMEN1TPSAB1ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL5208564 | 0.92 | TPSAB1 (0.37) | KMT2AMEN1GAAMAPTTPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5203155 | 0.91 | LPAR1 (0.38) | TPSAB1ALDH1A1LMNAPOLBHTT | |
| Trifluoroacetic Acid SCHEMBL5205693 | 0.91 | CSF1R (0.39) | KMT2ATPSAB1ALDH1A1HTTL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5201456 | 0.90 | ALDH1A1 (0.44) | KMT2AMEN1TPSAB1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5202835 | 0.90 | TPSAB1 (0.36) | KMT2ATPSAB1ALDH1A1LMNAPOLB | |
| Trifluoroacetic Acid SCHEMBL5203534 | 0.89 | KMT2A (0.37) | KMT2AMEN1MAPTTPSAB1POLB | |
| Trifluoroacetic Acid SCHEMBL5203223 | 0.89 | NAMPT (0.40) | KMT2AMEN1MAPTALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL5201746 | 0.88 | CACNA1B (0.36) | KMT2AMEN1TPSAB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |