⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070548 | 1.00 | — | — | |
| SCHEMBL3459825 | 1.00 | — | — | |
| SCHEMBL24462896 | 0.93 | LMNA (0.39) | — | |
| Iodide SCHEMBL8971179 | 0.88 | HIF1A (0.36) | — | |
| SCHEMBL13411703 | 0.87 | KDM4E (0.43) | — | |
| SCHEMBL15374908 | 0.81 | LMNA (0.43) | — | |
| SCHEMBL15374912 | 0.81 | LMNA (0.43) | — | |
| SCHEMBL15374906 | 0.81 | LMNA (0.43) | — | |
| SCHEMBL4778177 | 0.81 | THRB (0.40) | — | |
| SCHEMBL15835816 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3389783-A1 | NOVEL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-10-24 | — | — | EP | claimed |
| WO-2017106062-A1 | NOVEL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | claimed |
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |
| US-20210300940-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-09-30 | — | — | US | disclosed |
| US-10745356-B2 | Compositions and methods for treating tuberculosis | THE BROAD INSTITUTE, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190284140-A1 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | THE BROAD INSTITUTE, INC. | 2019-09-19 | — | — | US | disclosed |
| US-10329257-B2 | Compositions and methods for treating tuberculosis | THE BROAD INSTITUTE, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| WO-2017027768-A1 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | THE BROAD INSTITUTE, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20160326111-A1 | ARYL SUBSTITUTED INDOLES AND THE USE THEREOF | PURDUE PHARMA LP (US) | 2016-11-10 | — | — | US | disclosed |
| WO-2016079710-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| EP-1380121-B1 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070032487-A1 | Inhibitors of phosphatidylinositol 3-kinase | NOVARTIS AG (CH) | 2007-02-08 | — | — | US | disclosed |
| US-20070032487-A1 | Inhibitors of phosphatidylinositol 3-kinase | NOVARTIS AG (CH) | 2007-02-08 | — | — | US | disclosed |
| US-7087784-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN (US) | 2006-08-08 | — | — | US | disclosed |
| US-6887995-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040220407-A1 | Process to prepare oxazolidinones | PERRAULT WILLIAM R | 2004-11-04 | — | — | US | disclosed |
| EP-1380121-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20020169312-A1 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2002-11-14 | — | — | US | disclosed |
| WO-2002085849-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |