Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5207834 | 0.90 | PDE4D (0.41) | CNR2MAPTADORA1LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL5209515 | 0.88 | MAPT (0.40) | CNR2MAPTADORA1LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.88 | PDE4D (0.40) | CNR2MAPTADORA1LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5206983 | 0.87 | MAPT (0.41) | MAPTLMNAGAAPOLBTP53 | |
| Trifluoroacetic Acid SCHEMBL5208680 | 0.86 | KDM4E (0.36) | MAPTADORA1LMNAGAAPDE4D | |
| Trifluoroacetic Acid SCHEMBL5210732 | 0.84 | MAPT (0.35) | MAPTLMNAMEN1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL5210556 | 0.84 | CXCR2 (0.43) | LMNAMEN1KMT2ACXCR2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.83 | ALDH1A1 (0.40) | CNR2MAPTLMNAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.83 | ALDH1A1 (0.38) | CNR2MAPTLMNAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5205966 | 0.82 | PDE4D (0.39) | CNR2MAPTADORA1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |