Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5208680 | 0.95 | KDM4E (0.36) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.90 | PDE4D (0.41) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5209515 | 0.88 | MAPT (0.40) | MAPTKDM4EALDH1A1TP53HPGD | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.88 | PDE4D (0.40) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5206475 | 0.87 | PTGER4 (0.34) | MAPTALDH1A1TP53GAALMNA | |
| Trifluoroacetic Acid SCHEMBL5210556 | 0.87 | CXCR2 (0.43) | KDM4EALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL5210732 | 0.84 | MAPT (0.35) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5208832 | 0.83 | OPRM1 (0.35) | MAPTTP53HPGDTSHRHTT | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.83 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1TP53HPGD | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.83 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |