Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205778 | 0.93 | HTR1A (0.59) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5208063 | 0.90 | HTR1A (0.61) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5205085 | 0.90 | HTR1A (0.64) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5209548 | 0.88 | HTR1A (0.56) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6851258 | 0.86 | HTR1A (0.56) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5206598 | 0.85 | HTR1A (0.57) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5207387 | 0.85 | HTR1A (0.61) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5207130 | 0.82 | HTR1A (0.50) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5207392 | 0.81 | HTR1A (0.59) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL5202492 | 0.81 | HTR1A (0.74) | HTR1ASLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304324-B1 | SEROTONIN REUPTAKE INHIBITORS | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-6787560-B2 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030191126-A1 | Psychological disorders; antidepressants | SUMITOMO PHARMACEUTICALS COMPANY LIMITED | 2003-10-09 | — | — | US | disclosed |
| EP-1304324-A1 | SEROTONIN REUPTAKE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191126-A1 | Psychological disorders; antidepressants | CRH, HTR2C, HTR1A | HTR1A 3/4885SLC6A4 10/4885CYP2D6 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.