Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722083 | 0.78 | ALOX5 (0.56) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL10551323 | 0.78 | ALOX5 (0.56) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL6491739 | 0.77 | HIF1A (0.56) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL30389656 | 0.77 | KYNU (0.51) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL24951572 | 0.77 | SLC22A1 (0.59) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL8439197 | 0.77 | SLC22A1 (0.59) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL6491746 | 0.77 | SLC22A1 (0.59) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL10883562 | 0.76 | HIF1A (0.44) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL10723837 | 0.75 | HIF1A (0.54) | KYNUHIF1AADRB2ADRB1HTR1A | |
| SCHEMBL31415096 | 0.75 | KYNU (0.43) | KYNUHIF1AADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |