Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521187 | 0.90 | CYSLTR2 (0.55) | CYSLTR2HRH3ITGB3ITGA2BPTGES | |
| SCHEMBL5209887 | 0.90 | CYSLTR2 (0.56) | CYSLTR2HPGDSCN9A | |
| SCHEMBL5155579 | 0.87 | CYSLTR2 (0.44) | CYSLTR2HRH3ITGB3ITGA2BPTGES | |
| SCHEMBL13918423 | 0.87 | CYSLTR2 (0.55) | CYSLTR2HRH3PTGESALOX5KMT2A | |
| SCHEMBL5208674 | 0.86 | CYSLTR2 (0.43) | CYSLTR2HRH3MEN1KMT2AHPGD | |
| SCHEMBL4508597 | 0.85 | CYSLTR2 (0.49) | CYSLTR2HRH3ITGB3ITGA2BPTGES | |
| SCHEMBL13918435 | 0.85 | CYSLTR2 (0.48) | CYSLTR2HRH3ITGB3ITGA2BPTGES | |
| SCHEMBL5206606 | 0.84 | CYSLTR2 (0.47) | CYSLTR2PTGESALOX5SCN9A | |
| SCHEMBL13918351 | 0.82 | CYSLTR2 (0.68) | CYSLTR2HRH3MEN1KMT2AHPGD | |
| SCHEMBL5207067 | 0.81 | CYSLTR2 (0.55) | CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | claimed |
| EP-1572628-A1 | ISOPHTALIC ACID DERIVATIVES | Bayer HealthCare AG (DE) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052839-A1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | claimed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| EP-1572628-A1 | ISOPHTALIC ACID DERIVATIVES | Bayer HealthCare AG (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052839-A1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |