SCHEMBL5207072

SCHEMBL5207072

Cc1cc(OCCN(C)C)c(C(C)C)cc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 2/20 0.65
ADRA1A P35348 2/20 0.65
ADRA1B P35368 2/20 0.65
CHRNA4 P43681 2/20 0.65
CYP1A2 P05177 1/20 0.65
ADRA2A P08913 1/20 0.65
CYP2D6 P10635 1/20 0.65
PKM P14618 1/20 0.65
ADRA2B P18089 1/20 0.65
ADRA2C P18825 1/20 0.65
HTR2C P28335 1/20 0.65
HRH1 P35367 1/20 0.65
DRD3 P35462 1/20 0.65
OPRK1 P41145 1/20 0.65
HIF1A Q16665 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.64
BLM P54132 1/20 0.64
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29711062 0.98 SMN1; SMN2 (0.66) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
Acetic Acid SCHEMBL8961488 0.93 ADRA1D (0.69) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
Acetic Acid SCHEMBL11172121 0.92 SMN1; SMN2 (0.70) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
Moxisylyte SCHEMBL6398989 0.88 ADRA1D (0.88) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
Benzoic Acid SCHEMBL11129389 0.87 ADRA1D (0.58) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
SCHEMBL18272003 0.83 ADRA1D (0.50) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
SCHEMBL11132329 0.82 CYP1A2 (0.61) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
SCHEMBL10570677 0.82 ADRA1D (0.56) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
SCHEMBL10641890 0.81 ADRA1D (0.49) ADRA1DADRA1AADRA1BCHRNA4CYP1A2
SCHEMBL10671728 0.81 ADRA1D (0.49) ADRA1DADRA1AADRA1BCHRNA4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1018879-B1 NITROSATED AND NITROSYLATED ALPHA-ADRENERGIC RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS AND THEIR USES NITROMED INC (US) 2007-08-01 EP claimed
EP-0031184-B1 PROCESS FOR THE PREPARATION OF 4-(2-(DIMETHYLAMINO)-ETHOXY)-2-METHYL-5-(1-METHYLETHYL)-PHENOL ESTERS AND THEIR SALTS BLASCHIM S.p.A. (IT) 1985-07-10 EP claimed
JP-58126844-A None JP disclosed
JP-62111952-A None JP disclosed
JP-60115555-A None JP disclosed
JP-62053947-A None JP disclosed
JP-58167551-A None JP disclosed
JP-63063644-A None JP disclosed
JP-1228945-A None JP disclosed
JP-63141948-A None JP disclosed
JP-57206643-A None JP disclosed
JP-S5849342-A PREPARATION OF 5-(2-(DIMETHYLAMINO)ETHOXY)CARVACROL FUJIREBIO INC 1983-03-23 JP disclosed
JP-S5849343-A PREPARATION OF 5-(2-(DIMETHYLAMINO)ETHOXY)CARVACROL FUJIREBIO INC 1983-03-23 JP disclosed
JP-S5835149-A PREPARATION OF 5-(2-(DIMETHYLAMINO)ETHOXY)-CARVACROL FUJIREBIO INC 1983-03-01 JP disclosed
JP-S5835149-A PREPARATION OF 5-(2-(DIMETHYLAMINO)ETHOXY)-CARVACROL FUJIREBIO INC 1983-03-01 JP disclosed
JP-S57206643-A PREPARATION OF 5-(2-(DIMETHYLAMINO)ETHOXY)CARVACROL ACETATE FUJIREBIO INC 1982-12-18 JP disclosed
US-4336396-A Process for the preparation of 4-[2-(dimethylamino)-ethoxy]2-methyl-5-(1-methylethyl)-phenol esters and their salts BLASINACHIM S.P.A. (IT) 1982-06-22 US disclosed
JP-S5798243-A PREPARATION OF 5-(N-METHYLAMINOETHOXY)CARVACROL FUJIREBIO INC 1982-06-18 JP disclosed
EP-0031184-A1 Process for the preparation of 4-(2-(dimethylamino)-ethoxy)-2-methyl-5-(1-methylethyl)-phenol esters and their salts BLASCHIM S.p.A. (IT) 1981-07-01 EP disclosed
EP-0031184-A1 Process for the preparation of 4-(2-(dimethylamino)-ethoxy)-2-methyl-5-(1-methylethyl)-phenol esters and their salts BLASCHIM S.p.A. (IT) 1981-07-01 EP disclosed