Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344355 | 0.88 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL10641890 | 0.85 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL10671728 | 0.85 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| Methylamine SCHEMBL11339729 | 0.85 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL10706857 | 0.84 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| Dimethylamine SCHEMBL11221773 | 0.83 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL5207072 | 0.83 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL8961537 | 0.83 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| Hydrochloric Acid SCHEMBL29711062 | 0.81 | SMN1; SMN2 (0.66) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| Hydrochloric Acid SCHEMBL8924875 | 0.81 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016190871-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. (US) | 2016-12-01 | — | — | WO | disclosed |