Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 1/20 | 0.49 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.49 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.49 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.49 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.49 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.49 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.49 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18447775 | 0.84 | EGFR (0.49) | EGFRRPS6KB1LMNA | |
| SCHEMBL19205648 | 0.79 | ALDH1A1 (0.55) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL18449481 | 0.79 | ALDH1A1 (0.55) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL18483206 | 0.79 | ALDH1A1 (0.55) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11105495 | 0.78 | EGFR (0.52) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11105703 | 0.78 | EGFR (0.52) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL14670659 | 0.75 | EGFR (0.43) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11281906 | 0.75 | EGFR (0.52) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL2507116 | 0.74 | SCN1A (0.49) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17985414 | 0.74 | SCN1A (0.49) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513821-B1 | PROTEIN KINASE INHIBITORS | CYTOPIA PTY LTD (AU) | 2007-10-31 | — | — | EP | disclosed |