Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.41 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.41 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.41 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.41 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.41 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.41 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.41 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105460 | 0.86 | GALR3 (0.54) | EGFRLMNA | |
| SCHEMBL11105495 | 0.86 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11281906 | 0.80 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL5207074 | 0.78 | ATP1A1 (0.49) | EGFRRPS6KB1LMNACRHR1ATP1A1 | |
| SCHEMBL8024728 | 0.77 | EGFR (0.49) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11287675 | 0.77 | EGFR (0.49) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11104466 | 0.76 | MAOA (0.46) | LMNAKDM4E | |
| SCHEMBL11294004 | 0.75 | EGFR (0.39) | EGFRRPS6KB1LMNAP2RX3ATP1A1 | |
| SCHEMBL11110706 | 0.75 | GALR3 (0.51) | EGFRLMNA | |
| SCHEMBL11104154 | 0.75 | EGFR (0.53) | EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |