Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 2/20 | 0.31 |
| ▸ | RRM2 | P31350 | 2/20 | 0.31 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12086289 | 0.79 | KDM4E (0.35) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL14376297 | 0.79 | KDM4E (0.35) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL12404657 | 0.77 | CNR2 (0.39) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL10066634 | 0.77 | CYP2C9 (0.45) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL24785620 | 0.76 | EPHX1 (0.36) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL13932142 | 0.76 | RRM1 (0.33) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL13058289 | 0.76 | TSHR (0.37) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL13132822 | 0.76 | EPHX1 (0.36) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL19978872 | 0.74 | TSHR (0.35) | TSHR | |
| SCHEMBL24380351 | 0.74 | EPHX1 (0.41) | TSHRPRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958292-B1 | 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| US-6165944-A | 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0777658-B1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| US-5885934-A | HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |