Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207629 | 0.76 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5207705 | 0.74 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28493755 | 0.74 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28420567 | 0.73 | ALDH1A1 (0.65) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5202614 | 0.68 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28337082 | 0.68 | CES1 (0.77) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL762542 | 0.68 | CES1 (0.77) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11790630 | 0.68 | PIK3CD (0.51) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10463319 | 0.67 | MEN1 (0.63) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL819944 | 0.66 | TDP1 (0.64) | ALDH1A1MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |