Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843148 | 0.87 | POLB (0.32) | PPARGPPARA | |
| SCHEMBL348348 | 0.84 | LMNA (0.42) | ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL6887123 | 0.82 | — | — | |
| SCHEMBL258358 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL3673115 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL258639 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL258329 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL258262 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL2963165 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A | |
| SCHEMBL2971183 | 0.81 | KCNH2 (0.46) | KCNH2ALDH1A1LIPGPTPN1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |