Sugi Predict

Sugi Predict / Compounds / SCHEMBL5207774

SCHEMBL5207774

SCHEMBL5207774

[CH2]CC(=O)N(CCC)CCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.52
▸ HPGD P15428 1/20 0.52
▸ CA12 O43570 4/20 0.48
▸ CA9 Q16790 4/20 0.48
▸ CA2 P00918 3/20 0.48
▸ TSHR P16473 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ CA1 P00915 3/20 0.40
▸ TP53 P04637 1/20 0.40
▸ SIGMAR1 Q99720 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ MAPT P10636 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ MLYCD O95822 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206242 0.91 SIGMAR1 (0.49) ALDH1A1HPGDCA12CA9CA2
SCHEMBL5204543 0.90 CA12 (0.44) ALDH1A1HPGDCA12CA9CA2
SCHEMBL5209092 0.85 CA1 (0.52) ALDH1A1HPGDCA12CA9CA2
SCHEMBL6163385 0.83 CA12 (0.45) ALDH1A1HPGDCA12CA9CA2
SCHEMBL5208331 0.83 CA12 (0.42) ALDH1A1HPGDCA12CA9CA2
SCHEMBL6164439 0.81 CA12 (0.47) CA12CA9CA2CA1
SCHEMBL5147828 0.81 CA12 (0.47) CA12CA9CA2CA1
SCHEMBL6165557 0.81 CA12 (0.47) CA12CA9CA2CA1
SCHEMBL6161695 0.81 CA12 (0.47) CA12CA9CA2CA1
SCHEMBL6162339 0.81 CA12 (0.47) CA12CA9CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11938233-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2024-03-26 — — US disclosed
US-20220054671-A1 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2022-02-24 — — US disclosed
US-11191855-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2021-12-07 — — US disclosed
EP-3135110-B1 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME TRIOPTOTEC GMBH (DE) 2019-07-10 — — EP disclosed
US-20180272013-A1 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF UNIVERSITÄT SALZBURG (AT) 2018-09-27 — — US disclosed
WO-2017032892-A1 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODCUTION AND USE THEREOF UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2017-03-02 — — WO disclosed
EP-3135110-A1 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME Universitätsklinikum Regensburg (DE) 2017-03-01 — — EP disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 — — US disclosed
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 — — EP disclosed
EP-1055712-B1 Aqueous ink for ink jet recording MITSUI CHEMICALS INC (JP) 2005-02-16 — — EP disclosed
EP-0626174-A2 Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-30 — — EP disclosed
US-5352659-A Polypeptide; hypotensive agents TAKEDA CHEMICAL INDUSTRIES (JP) 1994-10-04 — — US disclosed
US-5306808-A Endothelin derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-26 — — US disclosed
EP-0547317-A1 Endothelin antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-23 — — EP disclosed
EP-0499266-A1 Endothelin antagonist TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-19 — — EP disclosed
EP-0470256-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1992-02-12 — — EP disclosed
WO-1991013089-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-05 — — WO disclosed
US-4988718-A Fungicides for plants BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 — — US disclosed
US-4968687-A AGRICULTURAL FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 — — US disclosed
EP-0359078-A1 Substituted heterocyclyl-oximino-pyrazolin-5-ones, method for their preparation and their use as herbicides BAYER AG (DE) 1990-03-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054671-A1 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF DHPS, SQLE, CYP51A1 ALDH1A1 103/4885HPGD 36/4885CA12 3178/4885
US-20180272013-A1 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF DHPS, SQLE, CYP51A1 ALDH1A1 103/4885HPGD 36/4885CA12 3178/4885
US-11191855-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof DHPS, SQLE, CYP51A1 ALDH1A1 103/4885HPGD 36/4885CA12 3178/4885
US-11938233-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof DHPS, SQLE, CYP51A1 ALDH1A1 103/4885HPGD 36/4885CA12 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.