Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211972 | 0.86 | TNKS (0.42) | TACR1FASNTNKSPARP1PARP2 | |
| SCHEMBL5212036 | 0.86 | TACR1 (0.46) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5210242 | 0.84 | TACR1 (0.47) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5214208 | 0.84 | TACR1 (0.46) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5213743 | 0.83 | TACR1 (0.49) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5212616 | 0.82 | TACR1 (0.45) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5207901 | 0.81 | CACNA2D1 (0.46) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5212688 | 0.81 | TACR1 (0.50) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL5209960 | 0.80 | TACR1 (0.49) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5210084 | 0.80 | TACR1 (0.46) | TACR1CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | TACR1 2372/4885CACNA2D1 4406/4885CACNA1B 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.