Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386106 | 0.79 | GPR119 (0.56) | GPR119 | |
| SCHEMBL386195 | 0.66 | GPR119 (0.74) | GPR119 | |
| SCHEMBL1673837 | 0.63 | GPR119 (0.53) | GPR119 | |
| SCHEMBL1673634 | 0.62 | GPR119 (0.75) | GPR119 | |
| SCHEMBL1673911 | 0.61 | GPR119 (0.60) | GPR119 | |
| SCHEMBL1674302 | 0.58 | GPR119 (0.52) | GPR119 | |
| SCHEMBL1673921 | 0.55 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14160288 | 0.54 | GPR119 (0.62) | GPR119 | |
| SCHEMBL4273005 | 0.53 | TTBK1 (0.54) | — | |
| SCHEMBL16071244 | 0.48 | LRRK2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758565-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | Arena Pharmaceuticals, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006076231-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | ARENA PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |