Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210164 | 0.92 | HRH3 (0.55) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL5210629 | 0.83 | HRH3 (0.57) | HRH3HSD11B1 | |
| SCHEMBL5211731 | 0.83 | HRH3 (0.58) | HRH3GNEHSD11B1 | |
| SCHEMBL5210438 | 0.83 | HRH3 (0.60) | HRH3HSD11B1 | |
| SCHEMBL5210990 | 0.78 | HRH3 (0.60) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL5212436 | 0.77 | HRH3 (0.59) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL5208546 | 0.76 | HRH3 (0.52) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL5209549 | 0.75 | L3MBTL3 (0.70) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL5213801 | 0.74 | HRH3 (0.56) | HRH3 | |
| SCHEMBL5212856 | 0.74 | L3MBTL3 (0.68) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |