Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210438 | 0.85 | HRH3 (0.60) | HRH3HSD11B1OGAMAP4K4 | |
| SCHEMBL5210476 | 0.83 | HRH3 (0.57) | HRH3HSD11B1OGA | |
| SCHEMBL5208501 | 0.83 | HRH3 (0.58) | HRH3HSD11B1 | |
| SCHEMBL5210164 | 0.80 | HRH3 (0.55) | HRH3 | |
| SCHEMBL5211791 | 0.78 | HRH3 (0.59) | HRH3 | |
| SCHEMBL5211397 | 0.78 | HRH3 (0.57) | HRH3 | |
| Hydrochloric Acid SCHEMBL5210768 | 0.77 | HRH3 (0.56) | HRH3 | |
| SCHEMBL5209775 | 0.76 | HRH3 (0.53) | HRH3 | |
| SCHEMBL14843580 | 0.73 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5209685 | 0.70 | HRH3 (0.75) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |