SCHEMBL123652

SCHEMBL123652

O=C(NC1CCCC1)c1ccc(C(=O)NC2CCCC2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.79
RAB9A P51151 7/20 0.79
SMN1; SMN2 Q16637 5/20 0.79
HPGD P15428 3/20 0.79
CYP1A2 P05177 1/20 0.79
CYP2C19 P33261 1/20 0.79
KMT2A Q03164 4/20 0.69
MAOA P21397 1/20 0.67
MAOB P27338 1/20 0.67
LMNA P02545 1/20 0.65
MEN1 O00255 1/20 0.63
ALDH1A1 P00352 3/20 0.63
MAPK1 P28482 1/20 0.63
PTPN1 P18031 1/20 0.61
PTPN11 Q06124 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
TP53 P04637 1/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL520877 0.98 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL28928584 0.98 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL126657 0.98 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517452 0.94 NPC1 (0.73) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29927547 0.92 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL518043 0.92 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL2920549 0.92 NPC1 (0.69) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517178 0.92 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL16584075 0.92 NPC1 (0.69) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517912 0.92 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
EP-4667512-A1 INCREASED AREA STRETCH RATIO FOR CAPACITOR FILMS MADE OF A BIAXIALLY ORIENTED POLYPROPYLENE FILM Borealis GmbH (AT) 2025-12-24 EP disclosed
WO-2025083226-A1 METHOD FOR ADDING ADDITIVES TO A POLYOLEFIN MELT OR A POLYOLEFIN SOLUTION BOREALIS AG (AT) 2025-04-24 WO disclosed
EP-4491396-A1 COMPOSITION COMPRISING POLYPROPYLENE AND CYCLIC OLEFIN POLYMER WITH IMPROVED DISPERSION PROPERTIES AND BREAKDOWN PERFORMANCE Borealis AG (AT) 2025-01-15 EP disclosed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
US-20240199865-A1 POLYPROPYLENE COMPOSITION FOR CABLE INSULATION BOREALIS AG (AT) 2024-06-20 US disclosed
US-20240158623-A1 POLYPROPYLENE COMPOSTION FOR CABLE INSULATION BOREALIS AG (AT) 2024-05-16 US disclosed
EP-3898237-B1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES BOREALIS AG (AT) 2024-04-17 EP disclosed
EP-4314152-A1 POLYPROPYLENE COMPOSITION FOR CABLE INSULATION Borealis AG (AT) 2024-02-07 EP disclosed
EP-4314153-A1 POLYPROPYLENE COMPOSITION FOR CABLE INSULATION Borealis AG (AT) 2024-02-07 EP disclosed
WO-2002094895-A1 PROPYLENE POLYMER PIPES FOR PIPELINES BOREALIS TECHNOLOGY OY (FI) 2002-11-28 WO disclosed
WO-2002094924-A1 POLYOLEFIN MULTILAYER PIPE BOREALIS TECHNOLOGY OY (FI) 2002-11-28 WO disclosed
WO-2002094922-A1 POLYOLEFIN COATED STEEL PIPES BOREALIS TECHNOLOGY OY (FI) 2002-11-28 WO disclosed
WO-2002094894-A1 PROPYLENE POLYMERS WITH IMPROVED PROPERTIES BOREALIS TECHNOLOGY OY (FI) 2002-11-28 WO disclosed
WO-2002094923-A1 INDUSTRIAL POLYOLEFIN PIPING SYSTEM BOREALIS TECHNOLOGY OY (FI) 2002-11-28 WO disclosed
EP-1260528-A1 Propylene polymer pipes for pipelines Borealis Technology OY (FI) 2002-11-27 EP disclosed
EP-1260545-A1 Industrial polyolefin piping system Borealis Technology OY (FI) 2002-11-27 EP disclosed
EP-1260546-A1 Polyolefin multilayer pipe Borealis Technology OY (FI) 2002-11-27 EP disclosed
EP-1260529-A1 Propylene polymers with improved properties Borealis Technology OY (FI) 2002-11-27 EP disclosed
EP-1260547-A1 Polyolefin coated steel pipes Borealis Technology OY (FI) 2002-11-27 EP disclosed