Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211180 | 0.89 | NPC1 (0.39) | F2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5207728 | 0.84 | NPC1 (0.43) | F2NPC1RAB9ASMN1; SMN2HPGD | |
| Trifluoroacetic Acid SCHEMBL6998476 | 0.83 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5209105 | 0.81 | TP53 (0.38) | F2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL6996710 | 0.80 | NPC1 (0.43) | F2NPC1RAB9ASMN1; SMN2HPGD | |
| Trifluoroacetic Acid SCHEMBL5210737 | 0.80 | F2 (0.38) | F2MAPTPRSS1CACNA1HCACNA1B | |
| Trifluoroacetic Acid SCHEMBL5207907 | 0.79 | MAPT (0.43) | F2NPC1RAB9ALMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL5208466 | 0.79 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL5204087 | 0.78 | LMNA (0.37) | F2LMNAMAPTPRSS1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5208806 | 0.78 | MAPT (0.37) | F2NPC1RAB9AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |