Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.60 |
| ▸ | CCR5 | P51681 | 16/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.44 |
| ▸ | CCR7 | P32248 | 2/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209291 | 0.92 | CCR2 (0.64) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL5209524 | 0.90 | CCR2 (0.73) | CCR2CCR5CXCR3CCR7 | |
| SCHEMBL6341404 | 0.90 | CCR2 (0.61) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL6347044 | 0.89 | CCR2 (0.60) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL5209375 | 0.88 | CCR2 (0.60) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL5206220 | 0.88 | CCR2 (0.61) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL5205469 | 0.87 | CCR2 (0.63) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL6351993 | 0.87 | CCR2 (0.58) | CCR2CCR5CXCR3CCR7 | |
| SCHEMBL6343987 | 0.87 | CCR2 (0.59) | CCR2CCR5CXCR3CCR7 | |
| SCHEMBL5209677 | 0.85 | CCR2 (0.58) | CCR2CCR5CXCR3CCR7CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |