SCHEMBL5209609

SCHEMBL5209609

[CH2]C(=O)NC(CC)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.38
TAS1R1 Q7RTX1 2/20 0.38
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP3 P08254 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.31
MMP8 P22894 1/20 0.31
CA9 Q16790 1/20 0.31
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
CPA1 P15085 1/20 0.31
ACE2 Q9BYF1 1/20 0.31
TSHR P16473 2/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5208547 0.84 ALDH1A1 (0.38) MMP1MMP2MMP3CA1CA2
SCHEMBL6722400 0.78 TAS1R3 (0.42) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL6722398 0.78 TAS1R3 (0.39) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL11915410 0.78 ALDH1A1 (0.40) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL8437778 0.78 ALDH1A1 (0.40) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL8435642 0.77 TAS1R3 (0.36) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL24444347 0.76 TAS1R3 (0.38) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL23479934 0.76 TAS1R3 (0.38) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL25098771 0.76 TAS1R3 (0.38) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL498535 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed
WO-1996005179-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed