Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21630425 | 1.00 | GABRA1 (0.53) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL7148942 | 0.86 | GABRA1 (0.51) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL7147579 | 0.86 | GABRA1 (0.51) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL9614879 | 0.84 | GABRA1 (0.49) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL9614880 | 0.84 | GABRA1 (0.49) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL28541380 | 0.82 | ACMSD (0.56) | ACMSDHPGDLMNAHTTMEN1 | |
| SCHEMBL9617330 | 0.80 | GABRA1 (0.45) | GABRA1GABRB2ACMSDALDH1A1HPGD | |
| SCHEMBL27956345 | 0.80 | ACMSD (0.54) | ACMSDHDAC4HDAC2HDAC8KMO | |
| SCHEMBL11595671 | 0.80 | ACMSD (0.54) | ACMSDHPGDLMNAHTTMEN1 | |
| SCHEMBL11161163 | 0.79 | ACMSD (0.57) | ACMSDHDAC4HDAC2HDAC8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232585-B | Single-component epoxy resin composition resistant to wet-hot hydrolysis, and preparation method and application thereof | 同济大学 | 2023-11-24 | — | — | CN | claimed |
| CN-115093567-B | Ultraviolet light curing resin composition based on thiol-ene reaction, and preparation method and application thereof | 同济大学 | 2023-08-04 | — | — | CN | claimed |
| CN-115232585-A | Single-component epoxy resin composition resistant to wet heat hydrolysis and preparation method and application thereof | 同济大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115232259-A | Wet-heat hydrolysis-resistant dual-curing resin composition and preparation method and application thereof | 同济大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115093567-A | Ultraviolet curing resin composition based on thiol-ene reaction and preparation method and application thereof | 同济大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115232259-B | Moisture-heat hydrolysis resistant dual-curing resin composition and preparation method and application thereof | 同济大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-115232585-B | Single-component epoxy resin composition resistant to wet-hot hydrolysis, and preparation method and application thereof | 同济大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-115093567-B | Ultraviolet light curing resin composition based on thiol-ene reaction, and preparation method and application thereof | 同济大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115232585-A | Single-component epoxy resin composition resistant to wet heat hydrolysis and preparation method and application thereof | 同济大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232259-A | Wet-heat hydrolysis-resistant dual-curing resin composition and preparation method and application thereof | 同济大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115093567-A | Ultraviolet curing resin composition based on thiol-ene reaction and preparation method and application thereof | 同济大学 | 2022-09-23 | — | — | CN | disclosed |
| EP-1194147-B1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2007-01-10 | — | — | EP | disclosed |
| US-6670474-B2 | Such as bis-1,2-(2-(2,3-epoxypropyl)phenoxy)ethane; chemical intermediates for formation of epoxy resins | PEWS R GARTH (US) | 2003-12-30 | — | — | US | disclosed |
| US-20020151731-A1 | Novel epoxide derivatives of allylarylphenols | PEWS R GARTH (US) | 2002-10-17 | — | — | US | disclosed |
| US-6465497-B2 | SUBSTITUTED 5-ARYL-2,4-THIAZOLIDINEDIONES AND OXAZOLIDINEDIONES; AGONISTS OF PPAR (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR); USEFUL TREATING DIABETES, HYPERGLYCEMIA, HYPERLIPIDEMIA, AND OBESITY | MERCK & CO., INC. | 2002-10-15 | — | — | US | disclosed |
| EP-1194147-A4 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6380191-B1 | FOR TREATMENT, CONTROL OR PREVENTION OF DIABETES, HYPERGLYCEMIA, HYPERLIPIDEMIA (INCLUDING HYPERCHOLESTEROLEMIA AND HYPERTRIGLYCERIDEMIA), ATHEROSCLEROSIS, OBESITY, VASCULAR RESTENOSIS | MERCK & CO. INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1194147-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| US-20020037911-A1 | Substituted 5-aryl-2,4-thiazolidinediones and oxazolidinediones; agonists of PPAR (Peroxisome proliferator activated receptor); useful treating diabetes, hyperglycemia, hyperlipidemia, and obesity | MERCK & CO., INC. | 2002-03-28 | — | — | US | disclosed |
| WO-2000078313-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037911-A1 | Substituted 5-aryl-2,4-thiazolidinediones and oxazolidinediones; agonists of PPAR (Peroxisome proliferator activated receptor); useful treating diabetes, hyperglycemia, hyperlipidemia, and obesity | PPARD, PPARA, PPARG | GABRA1 979/4885GABRB2 812/4885ACMSD 3109/4885 |
| US-20020151731-A1 | Novel epoxide derivatives of allylarylphenols | EPHX2, CBR3, CYP4X1 | GABRA1 2014/4885GABRB2 2055/4885ACMSD 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.