Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 6/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211659 | 0.93 | NPC1 (0.40) | PARP1PARP2TNKSGRIN2BMAPT | |
| SCHEMBL5212400 | 0.92 | TACR1 (0.39) | PARP1PARP2TNKSGRIN2BMAPT | |
| SCHEMBL5215079 | 0.89 | RAB9A (0.45) | PARP1PARP2TNKSMAPTLMNA | |
| SCHEMBL5210562 | 0.86 | HPGD (0.42) | PARP1PARP2TNKSGRIN2BMAPT | |
| SCHEMBL14610117 | 0.84 | PARP1 (0.38) | PARP1PARP2TNKSMAPT | |
| SCHEMBL5213389 | 0.84 | TNKS (0.38) | PARP1PARP2TNKSHPGD | |
| SCHEMBL5211394 | 0.84 | HDAC6 (0.42) | NAMPTMAPTLMNATSHRMAPK1 | |
| SCHEMBL5212004 | 0.83 | TACR1 (0.41) | PARP1PARP2TNKSGRIN2B | |
| SCHEMBL14609755 | 0.82 | TACR1 (0.43) | PARP1PARP2TNKS | |
| SCHEMBL5212284 | 0.82 | MEN1 (0.44) | PARP1PARP2TNKSALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | SCN9A 760/4885PARP1 4166/4885PARP2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.