Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL6950304 | 0.98 | SMN1; SMN2 (0.58) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Toluene SCHEMBL29111168 | 0.98 | SLC22A1 (0.54) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Tetrabuthylammonium SCHEMBL11246970 | 0.93 | SLC22A1 (0.55) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Tetrabuthylammonium SCHEMBL28869272 | 0.91 | SLC22A1 (0.52) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Tetrabuthylammonium SCHEMBL15453961 | 0.91 | SLC22A1 (0.52) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Tetrabuthylammonium SCHEMBL1724097 | 0.91 | SLC22A1 (0.52) | SLC22A1TP53SMN1; SMN2TSHRALOX12 | |
| Dodecane SCHEMBL28292270 | 0.91 | LMNA (0.58) | TP53SMN1; SMN2TSHRALOX12ALDH1A1 | |
| Heptane SCHEMBL27684378 | 0.91 | LMNA (0.58) | TP53SMN1; SMN2TSHRALOX12ALDH1A1 | |
| Decane SCHEMBL27778817 | 0.91 | LMNA (0.58) | TP53SMN1; SMN2TSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL10821326 | 0.89 | SLC22A1 (0.45) | SLC22A1TP53SMN1; SMN2TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015180585-A9 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | claimed |
| WO-2015180585-A1 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2015-12-03 | — | — | WO | claimed |
| WO-2015180585-A9 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | disclosed |
| WO-2015180585-A1 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2015-12-03 | — | — | WO | disclosed |
| EP-1187833-B1 | METHOD OF PRODUCING THIAMETHOXAM | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| US-6747146-B2 | USING PHASE TRANSFER CATALYST AND QUATERNARY AMMONIUM COMPOUND | SYNGENTA CROP PROTECTION, INC. | 2004-06-08 | — | — | US | disclosed |
| US-20030092915-A1 | Method of producing nitroguanidine- and nitroenamine derivatives | SYNGENTA CROP PROTECTION, INC. | 2003-05-15 | — | — | US | disclosed |
| EP-1187833-A1 | METHOD OF PRODUCING NITROGUANIDINE- AND NITROENAMINE DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000623-A1 | METHOD OF PRODUCING NITROGUANIDINE- AND NITROENAMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092915-A1 | Method of producing nitroguanidine- and nitroenamine derivatives | CBR1, CBR3, NOX1 | SLC22A1 2614/4885TP53 4701/4885SMN1; SMN2 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.