Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.61 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213158 | 0.83 | SCD (0.45) | SCDKDM4EALDH1A1MAPT | |
| SCHEMBL5213284 | 0.82 | SCD (0.51) | SCDALDH1A1MAPT | |
| SCHEMBL5216402 | 0.80 | SCD (0.47) | SCDTRPV1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL5212488 | 0.79 | SCD (0.48) | SCDKDM4EALDH1A1 | |
| SCHEMBL5214168 | 0.78 | SCD (0.41) | SCDKDM4EALDH1A1MAPT | |
| SCHEMBL5213811 | 0.77 | SCD (0.76) | SCDRBP4 | |
| SCHEMBL12285902 | 0.76 | SCD (1.00) | SCDRBP4 | |
| SCHEMBL2564090 | 0.74 | SCD (0.58) | SCDRBP4 | |
| SCHEMBL5215981 | 0.73 | SCD (0.37) | SCDTRPV1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL5215986 | 0.73 | SCD (0.37) | SCDTRPV1KDM4EALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | claimed |