Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216402 | 0.84 | SCD (0.47) | SCDKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5214168 | 0.80 | SCD (0.41) | SCDKDM4EALDH1A1LMNA | |
| SCHEMBL5210901 | 0.79 | SCD (0.61) | SCDKDM4EALDH1A1 | |
| SCHEMBL5213284 | 0.79 | SCD (0.51) | SCDPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5213158 | 0.77 | SCD (0.45) | SCDKDM4EMEN1KMT2AF10 | |
| SCHEMBL9664669 | 0.71 | GAA (0.47) | KDM4EPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5215981 | 0.69 | SCD (0.37) | SCDKDM4EALDH1A1 | |
| SCHEMBL5215986 | 0.69 | SCD (0.37) | SCDKDM4EALDH1A1 | |
| SCHEMBL10014259 | 0.67 | SMN1; SMN2 (0.50) | KDM4EPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6469067 | 0.67 | SMN1; SMN2 (0.50) | KDM4EPOLBSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |