Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212488 | 0.84 | SCD (0.48) | SCDALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5214168 | 0.81 | SCD (0.41) | SCDALDH1A1TP53RXFP1KDM4E | |
| SCHEMBL5213158 | 0.81 | SCD (0.45) | SCDALDH1A1TP53RXFP1KDM4E | |
| SCHEMBL5210901 | 0.80 | SCD (0.61) | SCDALDH1A1TRPV1KDM4ESIGMAR1 | |
| SCHEMBL5213284 | 0.78 | SCD (0.51) | SCDALDH1A1TP53RXFP1MALT1 | |
| SCHEMBL5215981 | 0.74 | SCD (0.37) | SCDALDH1A1TRPV1RXFP1KDM4E | |
| SCHEMBL5215986 | 0.74 | SCD (0.37) | SCDALDH1A1TRPV1RXFP1KDM4E | |
| SCHEMBL1476787 | 0.72 | SIGMAR1 (0.45) | ALDH1A1RXFP1KDM4ESIGMAR1KMT2A | |
| SCHEMBL5213370 | 0.71 | SCD (0.41) | SCDALDH1A1TRPV1RXFP1SIGMAR1 | |
| SCHEMBL5213218 | 0.69 | SCD (0.46) | SCDALDH1A1RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |